The ongoing worldwide effort to reduce animal numbers in research often omits the issue of pre-weaning mortality in mouse breeding. A conservative estimate of 20% mortality would mean approximately ...

Laboratory mice are typically housed in “shoebox” cages with limited opportunities to engage in natural behaviour. Temporary access to environments with increased space and complexity (playpens) may ...

A cage containing albino laboratory mice was one of more than 50 containers of the rodents stacked on shelves inside a clandestine lab discovered in a warehouse in downtown Reedley in December 2022.

For generations, laboratory mice have lived and died under fluorescent lights, their world reduced to plastic cages and standardized pellets. When researchers finally moved some of these animals into ...

The objective of this project was to introduce tunnel handling—a non-aversive alternative to tail handling—to mice during husbandry and routine handling procedures across a large facility with ...

The US National Library of Medicine (NLM) - National Institutes of Health (NIH) states that appropriate science and animal care operate simultaneously. A troubled or unwell animal does not yield the ...